BDBM50149275 2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indol-3-yl)-2-oxoacetic acid::CHEMBL325441::[1-Benzyl-5-(4-trifluoromethoxy-phenyl)-1H-indol-3-yl]-oxo-acetic acid::[{1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid
SMILES OC(=O)C(=O)c1cn(Cc2ccccc2)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=ODXQFEWQSHNQNI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50149275
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human plasminogen activator inhibitor-1More data for this Ligand-Target Pair
Affinity DataKd: 480nMAssay Description:Binding affinity of the compound to towards NBD-labeled S119C Plasminogen activator inhibitor-1 mutant in ratMore data for this Ligand-Target Pair
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity of compound towards latent Plasminogen activator inhibitor-1 expressed as apparent KdMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory concentration against Plasminogen activator inhibitor-1 by antibody assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of human non-glycosylated PAI1 using tissue type plasminogen activator substrate by direct chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of human Plasminogen activator inhibitor 1 using HRP substrate after 30 mins by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human glycosylated PAI1 using tissue type plasminogen activator substrate by direct chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human glycosylated PAI1 using urokinase type plasminogen activator substrate by direct chromogenic assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+4nMAssay Description:Binding affinity to human immobilized PAI1 by surface plasmon resonanceMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of vitronectin binding to human PAI1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PAI1 by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human non-glycosylated PAI1 using urokinase type plasminogen activator substrate by direct chromogenic assayMore data for this Ligand-Target Pair