BDBM50149564 CHEMBL3769584

SMILES CC(C)Oc1ccc(cc1Cl)-c1nnc(s1)-n1cc2CN(CCC(O)=O)CCc2n1

InChI Key InChIKey=JQULLGPZODCAFG-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149564   

TargetSphingosine 1-phosphate receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149564(CHEMBL3769584)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO-K1 EDG1 cells by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149564(CHEMBL3769584)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human S1P1 receptor expressed in RH7777 cells by [35S]GTP-gammaS accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149564(CHEMBL3769584)
Affinity DataEC50: <3.16E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in RBL cells by [35S]GTP-gammaS accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed