BDBM50150119 CHEMBL3769414
SMILES [H][C@@]12CCC[C@]1([H])N1C(=N2)N(C)C(=O)c2c(Nc3ccccc3)n(Cc3ccc(cc3)-c3cccc(F)n3)nc12
InChI Key InChIKey=BBIPVJCGIASXJB-PKTZIBPZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50150119
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 62nMAssay Description:Inhibition of recombinant full lenght human PDE4A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Inhibition of recombinant full lenght human PDE4A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 360nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 630nMAssay Description:Inhibition of recombinant full lenght human PDE5A using fluorescent labeled cGMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of recombinant full lenght human PDE11A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of recombinant full lenght human PDE10A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of recombinant full lenght human PDE8A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 3.10E+3nMAssay Description:Inhibition of recombinant full length human PDE3B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Inhibition of recombinant full lenght human PDE9A using fluorescent labeled cGMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of recombinant full length human PDE2A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Dart Neuroscience
Curated by ChEMBL
Dart Neuroscience
Curated by ChEMBL
Affinity DataIC50: 0.0580nMAssay Description:Inhibition of PDE1B (unknown origin)More data for this Ligand-Target Pair