BDBM50150238 CHEMBL3770107

SMILES [H][C@@]12CCC[C@]1([H])N1C(=N2)N(C)C(=O)c2c(Nc3ccccc3)n(Cc3ccc(nc3)C(F)(F)F)nc12

InChI Key InChIKey=HLJDFQMSWCGSIM-SJORKVTESA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50150238   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Intra-Cellular Therapies

Curated by ChEMBL
LigandPNGBDBM50150238(CHEMBL3770107)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of recombinant full lenght human PDE4A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Intra-Cellular Therapies

Curated by ChEMBL
LigandPNGBDBM50150238(CHEMBL3770107)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of recombinant full lenght human PDE5A using fluorescent labeled cGMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Intra-Cellular Therapies

Curated by ChEMBL
LigandPNGBDBM50150238(CHEMBL3770107)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Intra-Cellular Therapies

Curated by ChEMBL
LigandPNGBDBM50150238(CHEMBL3770107)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of recombinant full lenght human PDE10A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Intra-Cellular Therapies

Curated by ChEMBL
LigandPNGBDBM50150238(CHEMBL3770107)
Affinity DataKi:  4.20E+4nMAssay Description:Inhibition of recombinant full length human PDE3B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Intra-Cellular Therapies

Curated by ChEMBL
LigandPNGBDBM50150238(CHEMBL3770107)
Affinity DataKi:  7.20E+4nMAssay Description:Inhibition of recombinant full lenght human PDE11A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Intra-Cellular Therapies

Curated by ChEMBL
LigandPNGBDBM50150238(CHEMBL3770107)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of recombinant full length human PDE2A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50150238(CHEMBL3770107)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of recombinant full lenght human PDE8A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Intra-Cellular Therapies

Curated by ChEMBL
LigandPNGBDBM50150238(CHEMBL3770107)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of recombinant full lenght human PDE9A using fluorescent labeled cGMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed