BDBM50150335 (2R,4S)-6-[3-(4-{[(2,4-Difluoro-benzyl)-(3-methanesulfonylamino-2-methyl-phenyl)-amino]-methyl}-phenoxy)-phenoxy]-3,5-dihydroxy-hexanoic acid::CHEMBL182013

SMILES Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(Oc2cccc(OC[C@@H](O)C[C@@H](O)CC(O)=O)c2)cc1)Cc1ccc(F)cc1F

InChI Key InChIKey=BDFAGUJHMUVCCC-SXOMAYOGSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150335   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150335((2R,4S)-6-[3-(4-{[(2,4-Difluoro-benzyl)-(3-methane...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150335((2R,4S)-6-[3-(4-{[(2,4-Difluoro-benzyl)-(3-methane...)
Affinity DataIC50:  760nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150335((2R,4S)-6-[3-(4-{[(2,4-Difluoro-benzyl)-(3-methane...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed