BDBM50150340 (3R,5S)-6-[4-(4-{[Benzyl-(3-methanesulfonylamino-2-methyl-phenyl)-amino]-methyl}-phenoxy)-phenoxy]-3,5-dihydroxy-hexanoic acid::CHEMBL181759

SMILES Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Oc2ccc(OC[C@@H](O)C[C@@H](O)CC(O)=O)cc2)cc1

InChI Key InChIKey=DPFXGLNZSHRKPJ-IZLXSDGUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150340   

TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150340((3R,5S)-6-[4-(4-{[Benzyl-(3-methanesulfonylamino-2...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150340((3R,5S)-6-[4-(4-{[Benzyl-(3-methanesulfonylamino-2...)
Affinity DataIC50:  300nMAssay Description:Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150340((3R,5S)-6-[4-(4-{[Benzyl-(3-methanesulfonylamino-2...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed