BDBM50151533 4-{5-[(Z)-Cyclohexylimino]-4-methyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl}-benzamide::CHEMBL185446

SMILES Cn1nc(s\c1=N/C1CCCCC1)-c1ccc(cc1)C(N)=O

InChI Key InChIKey=ILHCAAUBKXDWAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50151533   

LigandPNGBDBM50151533(4-{5-[(Z)-Cyclohexylimino]-4-methyl-4,5-dihydro-[1...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151533(4-{5-[(Z)-Cyclohexylimino]-4-methyl-4,5-dihydro-[1...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human PDE4D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50151533(4-{5-[(Z)-Cyclohexylimino]-4-methyl-4,5-dihydro-[1...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of recombinant PDE7A1 (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151533(4-{5-[(Z)-Cyclohexylimino]-4-methyl-4,5-dihydro-[1...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of human Phosphodiesterase 4D3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed