BDBM50151628 8''-chlorospiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-2''-one::CHEMBL185460

SMILES Clc1cccc2c1NC(=O)NC21CCCCC1

InChI Key InChIKey=JYCHFFXFIDUIDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151628   

LigandPNGBDBM50151628(8''-chlorospiro[cyclohexane-1,4''-(1'',2'',3'',4''...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human PDE7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151628(8''-chlorospiro[cyclohexane-1,4''-(1'',2'',3'',4''...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151628(8''-chlorospiro[cyclohexane-1,4''-(1'',2'',3'',4''...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant PDE7 (unknown origin) expressed in Escherichia coli BL21 (DE3) using [3H]cAMP as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed