BDBM50151847 CHEMBL3775875

SMILES CN(C)C(=O)[C@H]1CC[C@H](Oc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)n2)CC1

InChI Key InChIKey=NIDQRYIFGQNUHN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50151847   

LigandChemical structure of BindingDB Monomer ID 50151847BDBM50151847(CHEMBL3775875)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sphaera Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151847BDBM50151847(CHEMBL3775875)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Sphaera Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151847BDBM50151847(CHEMBL3775875)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sphaera Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50151847BDBM50151847(CHEMBL3775875)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed