BDBM50152899 CHEMBL365031::N-Hydroxy-2-{1-methyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidin-3-yl}-acetamide
SMILES CN1CCCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1
InChI Key InChIKey=NGBXKQSVMZPDNE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50152899
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >2.10E+3nMAssay Description:Inhibition of Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >3.30E+3nMAssay Description:inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 3.87E+3nMAssay Description:Inhibition of Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >4.90E+3nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of porcine Tumor necrosis factor- alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 208nMAssay Description:Effect on TNF-Alpha release in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair