BDBM50153458 3-[1-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-4-phenylamino-pyrrole-2,5-dione::CHEMBL184649

SMILES CN(C)CCn1cc(C2=C(Nc3ccccc3)C(=O)NC2=O)c2ccccc12

InChI Key InChIKey=QJNCQEBQJXYHQL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50153458   

TargetProtein kinase C alpha type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153458(3-[1-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-4-phen...)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153458(3-[1-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-4-phen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))TBA
LigandPNGBDBM50153458(3-[1-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-4-phen...)
Affinity DataIC50:  28nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Homo sapiens (Human))TBA
LigandPNGBDBM50153458(3-[1-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-4-phen...)
Affinity DataIC50:  28nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Homo sapiens (Human))TBA
LigandPNGBDBM50153458(3-[1-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-4-phen...)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed