BDBM50153463 3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-phenylamino-pyrrole-2,5-dione::CHEMBL365656

SMILES CN(C)CCCn1cc(C2=C(Nc3ccccc3)C(=O)NC2=O)c2ccccc12

InChI Key InChIKey=AINIRABQPWWMRI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50153463   

TargetProtein kinase C alpha type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153463(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-phe...)
Affinity DataIC50:  460nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153463(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-phe...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153463(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-phe...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153463(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-phe...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153463(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-phe...)
Affinity DataIC50:  3.46E+3nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed