BDBM50153545 3-(2,6-Dichloro-phenyl)-5-[2-(3-methyl-2-oxo-imidazolidin-1-yl)-ethyl]-isoxazole-4-carboxylic acid (4-diethylamino-phenyl)-amide::CHEMBL182655

SMILES CCN(CC)c1ccc(NC(=O)c2c(CCN3CCN(C)C3=O)onc2-c2c(Cl)cccc2Cl)cc1

InChI Key InChIKey=MKQURHOQZHPDCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153545   

TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153545(3-(2,6-Dichloro-phenyl)-5-[2-(3-methyl-2-oxo-imida...)
Affinity DataIC50:  10nMAssay Description:Ability to inhibit ghrelin induced increase in intracellular [Ca2+] in CHO-K cells was determined by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153545(3-(2,6-Dichloro-phenyl)-5-[2-(3-methyl-2-oxo-imida...)
Affinity DataIC50:  21nMAssay Description:Ability to displace [125I]-ghrelin from cloned human GHS-R expressed in CHO-K cells was determined (Kd of ghrelin is 0.4 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed