BDBM50154291 CHEMBL3775181

SMILES Cc1oc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c2c1C(=O)N1CC[C@H](N)C1

InChI Key InChIKey=QTUNNMUQVOOHJL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50154291   

TargetMitogen-activated protein kinase kinase kinase 7(Human)
Mendeleyev University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50154291(CHEMBL3775181)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human MAP3K7 by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Mendeleyev University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50154291(CHEMBL3775181)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human MKNK1 by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Mendeleyev University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50154291(CHEMBL3775181)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human N-terminal GST-HIS6-tagged Aurora B expressed in sf9 cells by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetAurora kinase C(Human)
Mendeleyev University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50154291(CHEMBL3775181)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human N-terminal GST-HIS6-tagged Aurora C expressed in sf9 cells by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetDual serine/threonine and tyrosine protein kinase(Human)
Mendeleyev University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50154291(CHEMBL3775181)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human RIPK5 by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase tousled-like 1(Human)
Mendeleyev University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50154291(CHEMBL3775181)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human N-terminal FLAG, C-terminal HIS8-tagged TLK1 expressed in sf9 cells by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Mendeleyev University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50154291(CHEMBL3775181)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human N-terminal GST-HIS6-tagged PIM1 expressed in sf9 cells by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Mendeleyev University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50154291(CHEMBL3775181)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human N-terminal GST-HIS6-tagged PIM3 expressed in sf9 cells by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed