BDBM50154361 CHEMBL3775473

SMILES CC1(C)OC(=S)Nc2ccc(cc12)S(=O)(=O)N1c2ccccc2COc2cc(F)ccc12

InChI Key InChIKey=AXXQTTPUMYEBOV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50154361   

TargetCytochrome P450 3A4(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154361(CHEMBL3775473)
Affinity DataIC50: 363nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154361(CHEMBL3775473)
Affinity DataIC50: 397nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154361(CHEMBL3775473)
Affinity DataIC50: 651nMAssay Description:Inhibition of GST-tagged human glucocorticoid receptor LBD domain expressed in insect cells at by Gal4-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154361(CHEMBL3775473)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GST-tagged human progesterone receptor LBD domain expressed in insect cells by Gal4-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154361(CHEMBL3775473)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of estrogen receptor (unknown origin) by Gal4-based luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154361(CHEMBL3775473)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed