BDBM50154637 CHEMBL3774919

SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(nc12)-c1ccc(C)cc1

InChI Key InChIKey=WREPPILXFJFKRQ-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50154637   

TargetCannabinoid receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50154637(CHEMBL3774919)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50154637(CHEMBL3774919)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of [3H]CP-55,940 from human CB1 receptor expressed in CHO cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50154637(CHEMBL3774919)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of WIN 55,212-2 mediated suppression of forksolin induced c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50154637(CHEMBL3774919)
Affinity DataEC50:  652nMAssay Description:Inverse agonist activity at human CB2 receptor transfected in CHO cells assessed as increase in forksolin stimulated cAMP production by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed