BDBM50154932 CHEMBL3774632

SMILES CC(O)CNc1nc(NCc2ccc(cc2)-c2ccccn2)c2[nH]nc(C(C)C)c2n1

InChI Key InChIKey=BEMMPKXTCFGEAN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50154932   

TargetCyclin-dependent kinase 5(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50154932(CHEMBL3774632)
Affinity DataIC50:  5nMAssay Description:Inhibition of CDK5 (unknown origin) using histone H1 as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50154932(CHEMBL3774632)
Affinity DataIC50:  21nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in sf9 cells using histone H1 as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 1(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50154932(CHEMBL3774632)
Affinity DataIC50:  777nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 7(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50154932(CHEMBL3774632)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50154932(CHEMBL3774632)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 9(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50154932(CHEMBL3774632)
Affinity DataIC50:  240nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed