BDBM50155256 CHEMBL3775466

SMILES CN1CC[C@H](CCC\C=C\c2ccccc2-c2ccccc2)[C@H](C1)C(O)=O

InChI Key InChIKey=HERLKGKGEDDXSY-XPWWKEBLSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155256   

TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50155256(CHEMBL3775466)
Affinity DataKi:  7.24E+4nMAssay Description:Displacement of NO 711 from mouse GAT1 expressed in HEK293 cell membranes after 40 mins by LC-ESI-MS-MS-based MS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50155256(CHEMBL3775466)
Affinity DataIC50:  3.48E+4nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA/unlabeled GABA addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed