BDBM50155337 1-(4-{4-[2-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidin-1-yl)ethoxy]phenyl}but-3-yn-1-yl)-1-hydroxyurea::CHEMBL185905

SMILES NC(=O)N(O)CCC#Cc1ccc(OCCN2CCC(=C3c4ccc(Cl)cc4CCc4cccnc43)CC2)cc1

InChI Key InChIKey=TVGLBSUFYKPBIU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155337   

TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155337BDBM50155337(1-(4-{4-[2-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155337BDBM50155337(1-(4-{4-[2-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)
Affinity DataIC50: 185nMAssay Description:Inhibition of 5-lipoxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed