BDBM50155637 CHEMBL186295::Propan-2-one O-((S)-1-methyl-pyrrolidin-2-ylmethyl)-oxime

SMILES [#6]-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6]-[#8]\[#7]=[#6](\[#6])-[#6]

InChI Key InChIKey=XHBRUUSJRCHUBZ-VIFPVBQESA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50155637   

LigandPNGBDBM50155637(CHEMBL186295 | Propan-2-one O-((S)-1-methyl-pyrrol...)
Affinity DataKi:  520nMAssay Description:Inhibition of [3H]-epibatidine binding to alpha 4 beta 2 nicotinic acetylcholine receptor of rat cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50155637(CHEMBL186295 | Propan-2-one O-((S)-1-methyl-pyrrol...)
Affinity DataKi:  520nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50155637(CHEMBL186295 | Propan-2-one O-((S)-1-methyl-pyrrol...)
Affinity DataKi:  4.90E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50155637(CHEMBL186295 | Propan-2-one O-((S)-1-methyl-pyrrol...)
Affinity DataKi:  4.90E+4nMAssay Description:Inhibition of [125 I]-alpha Bungarotoxin binding to alpha 7 nicotinic acetylcholine receptor of rat cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed