BDBM50155730 1-[1-(2,2-Diphenyl-ethyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-ethanone::CHEMBL187525
SMILES COc1cc2CCN(C(CC(c3ccccc3)c3ccccc3)c2cc1OC)C(C)=O
InChI Key InChIKey=MYRDIKPCKNULKX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50155730
Affinity DataKi: 9.80nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to human melatonin receptor MT2 expressed in NIH3T3 rat fibroblast cellsMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to human melatonin receptor type 1A (MT1) expressed in NIH3T3 rat fibroblast cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Inhibitory concentration against Melatonin receptor type 1BMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Antagonist activity at MT2 receptor (unknown origin) assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at MT1 receptor (unknown origin) assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against Melatonin receptor type 1AMore data for this Ligand-Target Pair