BDBM50156670 2-(dimethylamino)-4,5,6,7-tetrabromo-1H-benzimidazole::4,5,6,7-TETRABROMO-N,N-DIMETHYL-1H-BENZIMIDAZOL-2-AMINE::CHEMBL376505
SMILES CN(C)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1
InChI Key InChIKey=SLPJGDQJLTYWCI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50156670
Affinity DataKi: 40nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Warsaw University Of Technology
Curated by ChEMBL
Warsaw University Of Technology
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Binding affinity to CK2alpha (unknown origin)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Warsaw University Of Technology
Curated by ChEMBL
Warsaw University Of Technology
Curated by ChEMBL
Affinity DataKi: 97nMAssay Description:Inhibition of human CK2 alpha catalytic subunit expressed in Escherichia coli BE21 (DE3) assessed as [33P]gamma-ATP incorporation into P2B substrate ...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
The John Paul Ii Catholic University Of Lublin
Curated by ChEMBL
The John Paul Ii Catholic University Of Lublin
Curated by ChEMBL
Affinity DataKi: 112nMAssay Description:Inhibition of human CK2 alpha' catalytic subunit expressed in Escherichia coli BL21 (DE3) assessed as [33P]gamma-ATP incorporation into P2B substrate...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
The John Paul Ii Catholic University Of Lublin
Curated by ChEMBL
The John Paul Ii Catholic University Of Lublin
Curated by ChEMBL
Affinity DataKi: 133nMAssay Description:Inhibition of human CK2 alpha' catalytic subunit expressed in Escherichia coli BE21 (DE3) assessed as [33P]gamma-ATP incorporation into RRRADDSDDDDD ...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Warsaw University Of Technology
Curated by ChEMBL
Warsaw University Of Technology
Curated by ChEMBL
Affinity DataKi: 139nMAssay Description:Inhibition of human CK2 alpha catalytic subunit expressed in Escherichia coli BL21 (DE3) assessed as [33P]gamma-ATP incorporation into RRRADDSDDDDD s...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Warsaw University Of Technology
Curated by ChEMBL
Warsaw University Of Technology
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:Inhibition of CK2alpha in human PLC1 cells using (Arg)3(Glu)3Thr(Glu)3 as substrate after 24 hrs in presence of [32P]gammaGTPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Università
Curated by ChEMBL
Università
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of MKK1More data for this Ligand-Target Pair
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of MAPKAPK1aMore data for this Ligand-Target Pair
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Università
Curated by ChEMBL
Università
Curated by ChEMBL
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant GST-tagged CK-2 using RRRADDSDDDDD as substrate incubated for 5 mins by scintillation counter analysisMore data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
University of Western Ontario
University of Western Ontario
Affinity DataKd: 36.4nMAssay Description:To assess direct binding of inhibitors to oxidized NQO2 (NQO2ox), fluorescence quenching of FAD was monitored with an excitation wavelength of 350 nm...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
University of Western Ontario
University of Western Ontario
Affinity DataIC50: 484nMAssay Description:To determine the IC50 value of each inhibitor, reactions were initiated by addition of 154 pM NQO2 to a reaction buffer containing 150 μM SCDP a...More data for this Ligand-Target Pair