BDBM50157136 1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one::1-(5-Furan-2-yl-oxazol-2-yl)-7-phenyl-heptan-1-one::CHEMBL177356

SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1ccco1

InChI Key InChIKey=TWQKSZUNMHKBKF-UHFFFAOYSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50157136   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157136(1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one...)
Affinity DataKi:  12nMAssay Description:Binding affinity against purified rat Fatty-acid amide hydrolase (FAAH) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157136(1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one...)
Affinity DataKi:  12nMAssay Description:Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157136(1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one...)
Affinity DataKi:  12nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157136(1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one...)
Affinity DataKi:  12nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157136(1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one...)
Affinity DataKi:  12nMpH: 9.0Assay Description:Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Homo sapiens (Human))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50157136(1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of KIAA1363 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50157136(1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one...)
Affinity DataIC50:  300nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157136(1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one...)
Affinity DataIC50:  12nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed