BDBM50157606 CHEMBL3785432
SMILES CCCS(=O)(=O)c1nc(NC2CC2)cc(n1)-c1ccc2n(ccc2c1)C1CC(C)(C)NC(C)(C)C1
InChI Key InChIKey=XVECNLUKQDKOST-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50157606
Affinity DataKd: 80nMAssay Description:Binding affinity to CERC2 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Binding affinity to CERC2 (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataKd: 79nMAssay Description:Binding affinity to CECR2 (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra-acetylate...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra-acetylate...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair