BDBM50158039 4-(6-Chloro-3-piperidin-4-yl-indole-1-sulfonyl)-phenylamine::CHEMBL178870

SMILES Nc1ccc(cc1)S(=O)(=O)n1cc(C2CCNCC2)c2ccc(Cl)cc12

InChI Key InChIKey=UYTCFMWLVJVLDP-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50158039   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158039(4-(6-Chloro-3-piperidin-4-yl-indole-1-sulfonyl)-ph...)
Affinity DataKi:  3nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158039(4-(6-Chloro-3-piperidin-4-yl-indole-1-sulfonyl)-ph...)
Affinity DataKi:  115nMAssay Description:Binding affinity against human cloned 5-hydroxytryptamine 1A receptor stably expressed in CHO cells using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158039(4-(6-Chloro-3-piperidin-4-yl-indole-1-sulfonyl)-ph...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity against human cloned 5-hydroxytryptamine 7 receptor stably expressed in CHO cells using [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158039(4-(6-Chloro-3-piperidin-4-yl-indole-1-sulfonyl)-ph...)
Affinity DataIC50:  8.5nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed