BDBM50158042 1-(5-Chloro-thiophene-2-sulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL178234

SMILES Clc1ccc(s1)S(=O)(=O)n1cc(C2=CCNCC2)c2ccccc12

InChI Key InChIKey=ZMARUYAGTVNWCS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158042   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158042(1-(5-Chloro-thiophene-2-sulfonyl)-3-(1,2,3,6-tetra...)
Affinity DataKi:  3nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158042(1-(5-Chloro-thiophene-2-sulfonyl)-3-(1,2,3,6-tetra...)
Affinity DataIC50:  14.1nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed