BDBM50158071 (2S,6R)-4-(4-Nitro-3-trifluoromethyl-phenyl)-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione::CHEMBL368906

SMILES Oc1c2C3CC(C=C3)c2c(O)n1-c1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

InChI Key InChIKey=LJBWEBKKYMAFTF-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50158071   

TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50158071((2S,6R)-4-(4-Nitro-3-trifluoromethyl-phenyl)-4-aza...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]-DHT binding to T877A androgen receptor of LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50158071((2S,6R)-4-(4-Nitro-3-trifluoromethyl-phenyl)-4-aza...)
Affinity DataKi:  55nMAssay Description:Inhibition of [3H]-DHT binding to androgen receptor of MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50158071((2S,6R)-4-(4-Nitro-3-trifluoromethyl-phenyl)-4-aza...)
Affinity DataIC50:  119nMAssay Description:Inhibition of human androgen receptor of breast carcinoma MDA-453 cells in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed