BDBM50158528 (S)-1-cyclohexyl-2-(furan-3-yl)-N-(2-(5-hydroxy-1H-indol-3-yl)-1-(thiazol-4-yl)ethyl)-1H-benzo[d]imidazole-5-carboxamide::1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H-indol-3-yl)-1-(thiazol-4-yl)ethyl)-1H-benzo[d]imidazole-5-carboxamide::CHEMBL376487

SMILES O=C(N[C@@H](Cc1c[nH]c2ccc(O)cc12)c1cscn1)c1ccc2c(c1)nc(-c1ccoc1)n2C1CCCCC1

InChI Key InChIKey=ZUDPNSAXFSEWCD-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50158528   

TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158528BDBM50158528(1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human liver CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158528BDBM50158528(1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H...)
Affinity DataIC50: 440nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158528BDBM50158528(1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human liver CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158528BDBM50158528(1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158528BDBM50158528(1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human liver CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158528BDBM50158528(1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158528BDBM50158528(1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158528BDBM50158528(1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human liver CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158528BDBM50158528(1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158528BDBM50158528(1-cyclohexyl-2-(furan-3-yl)-N-((S)-2-(5-hydroxy-1H...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human liver CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed