BDBM50158828 CHEMBL3786528
SMILES CCc1c(C)nc2c(cnn2c1OC)C#N
InChI Key InChIKey=NIROIUUITQXVHP-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50158828
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of recombinant full length FLAG-tagged KDM5A (unknown origin) expressed in sf9 cells using biotin-H3K4me3 (1 to 21 residues as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant His6-tagged KDM4C (350 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using H3K9me3 (1 to 21 resi...More data for this Ligand-Target Pair
Affinity DataIC50: 324nMAssay Description:Inhibition of KDM5A (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/1 uM 2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 324nMAssay Description:Inhibition of KDM5A (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/1 uM 2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of recombinant full length FLAG-tagged KDM5B (unknown origin) expressed in sf9 cells using biotin-H3K4me3 (1 to 21 residues as substrate p...More data for this Ligand-Target Pair