BDBM50158932 5-Pyridin-3-yl-pyrimidine::CHEMBL179762::US8609708, 77::cid_16654683

SMILES c1cncc(c1)-c1cncnc1

InChI Key InChIKey=KQMVCAXWHXEDPU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50158932   

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158932BDBM50158932(CHEMBL179762 | cid_16654683 | US8609708, 77 | 5-Py...)
Affinity DataKi:  2.74E+4nMAssay Description:Effect on coumarin 7-hydroxylation by human Cytochrome P-450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50158932BDBM50158932(CHEMBL179762 | cid_16654683 | US8609708, 77 | 5-Py...)
Affinity DataIC50: 1.00E+5nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158932BDBM50158932(CHEMBL179762 | cid_16654683 | US8609708, 77 | 5-Py...)
Affinity DataIC50: 1.65E+5nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent