BDBM50160488 1-Benzyl-2-(2-pyridin-3-yl-ethylsulfanyl)-1H-benzoimidazole-5-sulfonic acid 4-fluoro-benzylamide::CHEMBL183066::N-(4-fluorobenzyl)-1-benzyl-2-(2-(pyridin-3-yl)ethylthio)-1H-benzo[d]imidazole-5-sulfonamide

SMILES Fc1ccc(CNS(=O)(=O)c2ccc3n(Cc4ccccc4)c(SCCc4cccnc4)nc3c2)cc1

InChI Key InChIKey=ZPFRQGYBYZRNLU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50160488   

TargetGonadotropin-releasing hormone receptor(Rat)
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50160488(1-Benzyl-2-(2-pyridin-3-yl-ethylsulfanyl)-1H-benzo...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration of the compound towards rat leutinizing releasing hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGonadotropin-releasing hormone receptor(Human)
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50160488(1-Benzyl-2-(2-pyridin-3-yl-ethylsulfanyl)-1H-benzo...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration of the compound towards human leutinizing releasing hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGonadotropin-releasing hormone receptor(Human)
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50160488(1-Benzyl-2-(2-pyridin-3-yl-ethylsulfanyl)-1H-benzo...)
Affinity DataIC50:  120nMAssay Description:Binding affinity at human GnRH receptor by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGonadotropin-releasing hormone receptor(Rat)
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50160488(1-Benzyl-2-(2-pyridin-3-yl-ethylsulfanyl)-1H-benzo...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration towards rat leutinizing releasing hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGonadotropin-releasing hormone receptor(Human)
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50160488(1-Benzyl-2-(2-pyridin-3-yl-ethylsulfanyl)-1H-benzo...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration towards human leutinizing releasing hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed