BDBM50161883 4-Dimethylamino-but-2-enoic acid [4-(1-benzyl-1H-indol-5-ylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide::CHEMBL179652

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc4n(Cc5ccccc5)ccc4c3)c2cc1NC(=O)\C=C\CN(C)C

InChI Key InChIKey=YJFISNXQNZZQFP-DHZHZOJOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161883   

TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161883(4-Dimethylamino-but-2-enoic acid [4-(1-benzyl-1H-i...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161883(4-Dimethylamino-but-2-enoic acid [4-(1-benzyl-1H-i...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed