BDBM50163147 CHEMBL2310901::H-Tyr-Val-Nle-Gly-Pro-D-Nal(2'')-Arg-D-Nal-Asp-Arg-Phe-Gly-NH2

SMILES CCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O

InChI Key InChIKey=KWPBFXVTEVUNPD-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50163147   

TargetMelanocortin receptor 3(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163147BDBM50163147(H-Tyr-Val-Nle-Gly-Pro-D-Nal(2'')-Arg-D-Nal-Asp-Arg...)
Affinity DataEC50:  13nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 3 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163147BDBM50163147(H-Tyr-Val-Nle-Gly-Pro-D-Nal(2'')-Arg-D-Nal-Asp-Arg...)
Affinity DataEC50:  26nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 4 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163147BDBM50163147(H-Tyr-Val-Nle-Gly-Pro-D-Nal(2'')-Arg-D-Nal-Asp-Arg...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 3 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163147BDBM50163147(H-Tyr-Val-Nle-Gly-Pro-D-Nal(2'')-Arg-D-Nal-Asp-Arg...)
Affinity DataEC50:  55nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 1 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163147BDBM50163147(H-Tyr-Val-Nle-Gly-Pro-D-Nal(2'')-Arg-D-Nal-Asp-Arg...)
Affinity DataEC50:  250nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 5 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163147BDBM50163147(H-Tyr-Val-Nle-Gly-Pro-D-Nal(2'')-Arg-D-Nal-Asp-Arg...)
Affinity DataIC50: 350nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 5 receptor expressed in HEK293 cells; N = 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163147BDBM50163147(H-Tyr-Val-Nle-Gly-Pro-D-Nal(2'')-Arg-D-Nal-Asp-Arg...)
Affinity DataIC50: 350nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 4 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163147BDBM50163147(H-Tyr-Val-Nle-Gly-Pro-D-Nal(2'')-Arg-D-Nal-Asp-Arg...)
Affinity DataIC50: 350nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed