BDBM50163460 2-Amino-6-(2-hydroxy-ethylsulfanyl)-4-(3-trifluoromethyl-phenyl)-pyridine-3,5-dicarbonitrile::CHEMBL359833

SMILES Nc1nc(SCCO)c(C#N)c(-c2cccc(c2)C(F)(F)F)c1C#N

InChI Key InChIKey=RVRYVGRACLJCOC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163460   

TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM50163460(2-Amino-6-(2-hydroxy-ethylsulfanyl)-4-(3-trifluoro...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM50163460(2-Amino-6-(2-hydroxy-ethylsulfanyl)-4-(3-trifluoro...)
Affinity DataKi:  14.1nMAssay Description:Antagonist activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed