BDBM50164474 2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl}-5-methyl-phenylamine::CHEMBL192528

SMILES Cc1ccc(Sc2ccccc2CNCCF)c(N)c1

InChI Key InChIKey=OGVZXKWRLUGGKA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164474   

TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164474(2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl...)
Affinity DataKi:  71.3nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164474(2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl...)
Affinity DataKi:  3.91E+3nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164474(2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl...)
Affinity DataKi:  4.43E+3nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed