BDBM50165161 CHEMBL386768::CHEMBL413647::Radiolabeled octreotide derivative

SMILES C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)CN2CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1

InChI Key InChIKey=RZHKDBRREKOZEW-UHFFFAOYSA-K

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50165161   

TargetSomatostatin receptor type 2(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165161(CHEMBL413647 | CHEMBL386768 | Radiolabeled octreot...)
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 2 expressed in CCL39 cells; (n=7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165161(CHEMBL413647 | CHEMBL386768 | Radiolabeled octreot...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 2 expressed in CCL39 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165161(CHEMBL413647 | CHEMBL386768 | Radiolabeled octreot...)
Affinity DataIC50: 73nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 5 expressed in CHO-K1 cells; (n=6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165161(CHEMBL413647 | CHEMBL386768 | Radiolabeled octreot...)
Affinity DataIC50: 114nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 5 expressed in CHO-K1 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165161(CHEMBL413647 | CHEMBL386768 | Radiolabeled octreot...)
Affinity DataIC50: 389nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 3 expressed in CCL39 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165161(CHEMBL413647 | CHEMBL386768 | Radiolabeled octreot...)
Affinity DataIC50: 613nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 3 expressed in CCL39 cells; (n=7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165161(CHEMBL413647 | CHEMBL386768 | Radiolabeled octreot...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 4 expressed in CCL39 cells; (n=6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165161(CHEMBL413647 | CHEMBL386768 | Radiolabeled octreot...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 1 expressed in CHO-K1 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165161(CHEMBL413647 | CHEMBL386768 | Radiolabeled octreot...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 4 expressed in CCL39 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165161(CHEMBL413647 | CHEMBL386768 | Radiolabeled octreot...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 1 expressed in CHO-K1 cells; (n=6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed