BDBM50165312 9-(2-Isopropoxy-ethyl)-8-(3-methoxy-phenylsulfanyl)-9H-purin-6-ylamine::CHEMBL191601
SMILES COc1cccc(Sc2nc3c(N)ncnc3n2CCOC(C)C)c1
InChI Key InChIKey=KPMKUCGAUSWIBL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50165312
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataIC50: 4.76E+4nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.80E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair