BDBM50165372 CHEMBL3798837

SMILES CCc1cc(cc(C)c1OC[C@@H](O)CNC(=O)CO)-c1noc(n1)-c1cc(C)c(CN(C)CC(C)C)s1

InChI Key InChIKey=GHEKPOPATTZHPU-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50165372   

TargetSphingosine 1-phosphate receptor 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50165372(CHEMBL3798837)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human recombinant S1PR1 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding preincubated for 30 mins followed by [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50165372(CHEMBL3798837)
Affinity DataEC50:  145nMAssay Description:Agonist activity at human recombinant S1PR3 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding preincubated for 30 mins followed by [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50165372(CHEMBL3798837)
Affinity DataEC50:  753nMAssay Description:Agonist activity at S1PR5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50165372(CHEMBL3798837)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at S1PR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50165372(CHEMBL3798837)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at S1PR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed