BDBM50166610 CHEMBL3800526

SMILES COc1cc(CCc2cc(Nc3ncnc4cc(ccc34)N3CCN4CCCCC4C3)n[nH]2)cc(OC)c1

InChI Key InChIKey=OCMFTUJIRAAZFF-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50166610   

TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166610(CHEMBL3800526)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FGFR3 in human RT112 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166610(CHEMBL3800526)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166610(CHEMBL3800526)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FGFR1 in human KG1 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166610(CHEMBL3800526)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of FGFR2 in human KATO III cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166610(CHEMBL3800526)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FGFR1 in human H1581 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166610(CHEMBL3800526)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant FGFR2 in human SNU16 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166610(CHEMBL3800526)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166610(CHEMBL3800526)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant FGFR3 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166610(CHEMBL3800526)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166610(CHEMBL3800526)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant FGFR4 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed