BDBM50167280 CHEMBL3797259

SMILES OCCNC(=O)c1ccc(cc1)-n1c2cn[nH]c2c2cc(F)ccc12

InChI Key InChIKey=RZXSROGFHJQWNH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50167280   

TargetMicrotubule-associated protein 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50167280(CHEMBL3797259)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of human MetAP2 in HUVEC cells assessed as accumulation of N-Met 14-3-3gamma after 24 hrs by western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50167280(CHEMBL3797259)
Affinity DataIC50:  7.94E+3nMAssay Description:Inhibition of human CYP1A2 expressed in Escherichia coli DH5alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMicrotubule-associated protein 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50167280(CHEMBL3797259)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed