BDBM50167706 (S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-3-methyl-4-oxo-4H-chromene-2-carboxamide::3-Methyl-4-oxo-4H-chromene-2-carboxylic acid ((S)-1-benzyl-2-carbamoyl-2-oxo-ethyl)-amide::CHEMBL195728

SMILES Cc1c(oc2ccccc2c1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(N)=O

InChI Key InChIKey=GTQCEBKREVJDGA-HNNXBMFYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50167706   

TargetCalpain-1 catalytic subunit(Human)
Institute of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50167706((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-3-met...)
Affinity DataIC50:  240nMAssay Description:Inhibitory concentration against human plasma mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Human)
Institute of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50167706((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-3-met...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human erythrocytes mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Human)
Institute of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50167706((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-3-met...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimeteryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Human)
Institute of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50167706((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-3-met...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed