BDBM50168746 (2R,3R)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL187245

SMILES C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2cccc(Cl)c2)cc1

InChI Key InChIKey=LOQCMKWGWBMVPA-AZUAARDMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50168746   

LigandPNGBDBM50168746((2R,3R)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50168746((2R,3R)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50:  851nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50168746((2R,3R)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50:  860nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed