BDBM50169475 4-{3-[2-(1H-Indol-3-yl)-ethylsulfanyl]-5-quinolin-2-yl-[1,2,4]triazol-4-yl}-butylamine::CHEMBL191025

SMILES NCCCCn1c(SCCc2c[nH]c3ccccc23)nnc1-c1ccc2ccccc2n1

InChI Key InChIKey=RTTXVNCHGUKGPN-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50169475   

TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169475BDBM50169475(4-{3-[2-(1H-Indol-3-yl)-ethylsulfanyl]-5-quinolin-...)
Affinity DataKi:  10nMAssay Description:Inhibitory constant against human sst5 receptor at a dose of 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169475BDBM50169475(4-{3-[2-(1H-Indol-3-yl)-ethylsulfanyl]-5-quinolin-...)
Affinity DataKi:  12nMAssay Description:Inhibitory constant against human sst2 receptor at a dose of 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169475BDBM50169475(4-{3-[2-(1H-Indol-3-yl)-ethylsulfanyl]-5-quinolin-...)
Affinity DataKi:  41nMAssay Description:Displacement of [125I]-Tyr- SRIF-14 from human SST-2A assessed as inhibition constant incubated for 90 mins by gamma counter based competitive radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169475BDBM50169475(4-{3-[2-(1H-Indol-3-yl)-ethylsulfanyl]-5-quinolin-...)
Affinity DataKi:  51nMAssay Description:Binding affinity to human SST5 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSomatostatin receptor type 4(Human)
Southern Illinois University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169475BDBM50169475(4-{3-[2-(1H-Indol-3-yl)-ethylsulfanyl]-5-quinolin-...)
Affinity DataKi:  83nMAssay Description:Displacement of [125I]-Tyr- SRIF-14 from human SST4 assessed as inhibition constant incubated for 90 mins by gamma counter based competitive radiolig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSomatostatin receptor type 3(Human)
Southern Illinois University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169475BDBM50169475(4-{3-[2-(1H-Indol-3-yl)-ethylsulfanyl]-5-quinolin-...)
Affinity DataKi:  386nMAssay Description:Binding affinity to human SST3 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed