BDBM50169842 1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophenylsulfonyl)piperidine::1-[2-(2,4-Difluoro-phenyl)-ethyl]-4-fluoro-4-(4-fluoro-benzenesulfonyl)-piperidine::CHEMBL175832

SMILES Fc1ccc(cc1)S(=O)(=O)C1(F)CCN(CCc2ccc(F)cc2F)CC1

InChI Key InChIKey=VDURQHWFSXZAER-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50169842   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity against human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  0.630nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  176nMAssay Description:Binding affinity against human 5-hydroxytryptamine 2c receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]mesurgeline from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  313nMAssay Description:Binding affinity against human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  5.56E+3nMAssay Description:Binding affinity against human IKr channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  5.56E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169842(1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...)
Affinity DataKi:  5.60E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed