BDBM50170138 1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione::1-benzyl-7-ethyl-6-methyl-3-propyl-1H-imidazo[1,2-a]purine-2,4(3H,8H)-dione::CHEMBL373090

SMILES CCCn1c(=O)n(Cc2ccccc2)c2nc3[nH]c(CC)c(C)n3c2c1=O

InChI Key InChIKey=HXRUQROKFKMUEI-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50170138   

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170138(1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]MRE3008F20 from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170138(1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataKi:  60nMAssay Description:Inhibition of [3H]-MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; range is 53 to 69 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170138(1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human cloned adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170138(1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-DPCPX binding to human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170138(1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ZM 241385 binding to human adenosine A2a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170138(1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170138(1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of 100 nM NECA-stimulated cAMP production in CHO cells expressing human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170138(1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human cloned adenosine A2B cells expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed