BDBM50170576 1-(4-{1-[4-(2,3-Dihydroxy-propylamino)-3-methyl-phenyl]-1-ethyl-propyl}-2-methyl-phenoxy)-3,3-dimethyl-butan-2-one::CHEMBL199238

SMILES CCC(CC)(c1ccc(NCC(O)CO)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1

InChI Key InChIKey=YUHGPRDTZYLKEH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170576   

TargetAndrogen receptor(Mouse)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50170576(1-(4-{1-[4-(2,3-Dihydroxy-propylamino)-3-methyl-ph...)
Affinity DataIC50: 7.60nMAssay Description:Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50170576(1-(4-{1-[4-(2,3-Dihydroxy-propylamino)-3-methyl-ph...)
Affinity DataKi:  1.17E+3nMAssay Description:Binding affinity to androgen receptor by incubation with GST-hARLBD and [3H]testosteroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed