BDBM50170604 CHEMBL3805585

SMILES Oc1c2C(=O)N3CCCN3Cc2c(C#N)c2cc(Cc3cccc(Cl)c3F)cnc12

InChI Key InChIKey=CYJVKJHOTQQQQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170604   

TargetIntegrase(Human immunodeficiency virus type 1)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50170604(CHEMBL3805585)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50170604(CHEMBL3805585)
Affinity DataIC50: 415nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed