BDBM50170908 CHEMBL3805115

SMILES ON1C(=O)C(C(=O)NC2CCCCC2)c2ccccc2C1=O

InChI Key InChIKey=LTUWOTPOUIFCEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170908   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50170908(CHEMBL3805115 | US20250213569, Compound 115)
Affinity DataIC50: 700nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50170908(CHEMBL3805115 | US20250213569, Compound 115)
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2017
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
New York University

US Patent
LigandPNGBDBM50170908(CHEMBL3805115 | US20250213569, Compound 115)
Affinity DataIC50: 1.46E+5nMAssay Description:Commercially available 2-Hydroxyisoquinoline-1,3(2H,4H)-dione (CAS No: 6890-08-0), a well-known scaffold backbone used to develop human immunodeficie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent