BDBM50171860 ((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL363424
SMILES CCOP(=O)(N1Cc2ccccc2C[C@@H]1C(=O)NO)c1ccc(OC)cc1
InChI Key InChIKey=RBLCSCFFNCADJO-XZATXCMXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50171860
Affinity DataKi: 4.60nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
North Dakota State University
Curated by ChEMBL
North Dakota State University
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of MOCAc-Pro-Leu-Gly-Leu-A2p (Dnp)-Ala-Arg-NH2 binding to human matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
North Dakota State University
Curated by ChEMBL
North Dakota State University
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
North Dakota State University
Curated by ChEMBL
North Dakota State University
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Inhibition of Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
North Dakota State University
Curated by ChEMBL
North Dakota State University
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Inhibition constant for human matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
North Dakota State University
Curated by ChEMBL
North Dakota State University
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Inhibition of recombinant human Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Inhibition of recombinant human Matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Organon K.K.
Curated by ChEMBL
Organon K.K.
Curated by ChEMBL
Affinity DataKi: 7.20nMAssay Description:Inhibition of recombinant human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: >650nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
Affinity DataKi: >650nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
North Dakota State University
Curated by ChEMBL
North Dakota State University
Curated by ChEMBL
Affinity DataKi: >800nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
North Dakota State University
Curated by ChEMBL
North Dakota State University
Curated by ChEMBL
Affinity DataKi: >800nMAssay Description:Inhibition of Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
Affinity DataKi: >850nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
Affinity DataKi: >850nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Organon K.K.
Curated by ChEMBL
Organon K.K.
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of heparin-binding epidermal growth factor (HB-EGF) sheddingMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Organon K.K.
Curated by ChEMBL
Organon K.K.
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of heparin-binding epidermal growth factor (HB-EGF) sheddingMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:In vitro amphiregulin shedding inhibitionMore data for this Ligand-Target Pair