BDBM50171991 5-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acid::CHEMBL190968

SMILES CCC1(Cc2cc(OCCCOc3ccc(cc3Cl)C(C)(C)C)ccc2O1)C(O)=O

InChI Key InChIKey=HHBHDUVYOAOZPO-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50171991   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171991(5-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-et...)
Affinity DataEC50:  9nMAssay Description:Effective concentration against human PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Dog)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171991(5-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-et...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171991(5-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-et...)
Affinity DataEC50:  280nMAssay Description:Effective concentration against hamster PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171991(5-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-et...)
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro binding affinity for PPAR-gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171991(5-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-et...)
Affinity DataIC50: 4.33E+3nMAssay Description:In vitro binding affinity for PPAR-gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171991(5-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-et...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity for PPAR-deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed